Endocrine Abstracts

Background and purpose: Type 1 myotonic dystrophy (MD), associates neuromuscular, cardiac, respiratory and endocrine disorders. The aim of this study was to determine the prevalence of thyroid disorders and of any causal factors.Methods: A retrospective single centre study was conducted, between 2000 and 2016, in 127 MD patients, diagnosed by familial genetic screening after informed consent. Clinical examination, TSH assay, 120-min glucose and insulin l...

Introduction: Anti-thyrotropin receptor antibodies (TSHR-Abs) stimulating the thyroid (TSAb) are responsible for Graves’ disease. In some patients, the TSHR-Abs can block thyrotropin action (TBAb) and cause hypothyroidism, the switch between stimulating and blocking activity in Graves’ disease being well. This reports aims to describe clinical presentation of patients affected directly by hypothyroidism.Material and methods: Retrospective clini...